SB-216641A

Catalog No.: A45880
5-HT1B/D Antagonist
SB-216641A is a selective antagonist of the 5-HT1B and 5-HT1D receptors. This compound exhibits high affinity and specificity for the human 5-HT1B receptor while demonstrating minimal activity at the 5-HT1D receptor. SB-216641A is utilized in research applications aimed at understanding serotonergic signaling and the modulation of neuropsychological disorders. Additionally, it has been shown to inhibit the function of SKF-99101H, providing insights into receptor interactions and pharmacological effects.
Grouped product items
Size Price Stock Qty
1mg
$30.00
In stock
5mg
$75.00
In stock
10mg
$110.00
In stock
25mg
$190.00
In stock
50mg
$275.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSB-216641A is a selective antagonist of the 5-HT1B and 5-HT1D receptors. This compound exhibits high affinity and specificity for the human 5-HT1B receptor while demonstrating minimal activity at the 5-HT1D receptor. SB-216641A is utilized in research applications aimed at understanding serotonergic signaling and the modulation of neuropsychological disorders. Additionally, it has been shown to inhibit the function of SKF-99101H, providing insights into receptor interactions and pharmacological effects.
Product Information
Catalog NumA45880
FormulaC28H31ClN4O4
Molecular Weight523.02
CAS Number193611-67-5
SMILESO=C(C1=CC=C(C2=C(C)C=C(C3=NOC(C)=N3)C=C2)C=C1)NC4=CC=C(C(OCCN(C)C)=C4)OC.Cl
SynonymsSB-216641 hydrochloride
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