SB-221284 is a selective antagonist of the 5-HT2C and 5-HT2B receptors, exhibiting pKi values of 6.4, 7.9, and 8.6 for the 5-HT2A, 5-HT2B, and 5-HT2C receptors, respectively. This compound is valuable in studying the role of serotonergic signaling in neurological diseases and may contribute to the development of therapeutic strategies targeting these receptors. Its specificity makes it a useful tool for researching the physiological and pathological functions associated with serotonin receptors.
SB-221284 is a selective antagonist of the 5-HT2C and 5-HT2B receptors, exhibiting pKi values of 6.4, 7.9, and 8.6 for the 5-HT2A, 5-HT2B, and 5-HT2C receptors, respectively. This compound is valuable in studying the role of serotonergic signaling in neurological diseases and may contribute to the development of therapeutic strategies targeting these receptors. Its specificity makes it a useful tool for researching the physiological and pathological functions associated with serotonin receptors.
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