Fig. 1 · Structure
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SB-224289
5-HT Receptor Antagonist
SB-224289 is a selective antagonist of the 5-HT1B receptor, primarily involved in the modulation of serotonin signaling pathways. Its antagonistic properties contribute to its anxiolytic effects, making it relevant in research focused on anxiety disorders and neuropharmacology. This compound serves as a valuable tool for studying serotonin-related pathways and the development of potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 180083-23-2 |
| Applications | 5-HT Receptor Antagonist |
| Formula | C32H32N4O3 |
| Molecular Weight | 520.62 |
| SMILES | O=C(C1=CC=C(C2=CC=C(C3=NOC(C)=N3)C=C2C)C=C1)N4CCC5=C4C=C6C(OCC67CCN(C)CC7)=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.