SB-743921 free base

Name: SB-743921 free base
Brand: Adooq Bioscience
SKU: A54750
Rating: 5 (288 reviews)

Catalog No.: A54750

Eg5 Inhibitor

SB-743921 free base is a highly selective inhibitor of the mitotic kinesin Eg5, exhibiting a Ki of 0.1 nM. This compound effectively induces mitotic arrest, inhibits cell cycle progression, and promotes apoptosis. It serves as a valuable tool in cancer research, particularly in the study of myeloma, leukemia, and other malignancies.

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SB-743921 free base 618430-39-0 Eg5 Inhibitor

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Grouped product items
Size	Price	Stock
25mg	$1,655.00	In stock
50mg	$2,115.00	In stock
100mg	$2,720.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	SB-743921 free base is a highly selective inhibitor of the mitotic kinesin Eg5, exhibiting a Ki of 0.1 nM. This compound effectively induces mitotic arrest, inhibits cell cycle progression, and promotes apoptosis. It serves as a valuable tool in cancer research, particularly in the study of myeloma, leukemia, and other malignancies.

Product Information

Catalog Num	A54750
Formula	C31H33ClN2O3
Molecular Weight	517.06
CAS Number	618430-39-0
SMILES	O=C1C(CC2=CC=CC=C2)=C([C@@H](C(C)C)N(C(C3=CC=C(C)C=C3)=O)CCCN)OC4=CC(Cl)=CC=C41

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