Fig. 1 · Structure

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SB02024

Vps34 Inhibitor

SB02024 is a potent inhibitor of Vps34, a kinase involved in autophagy and cellular trafficking. This compound effectively inhibits Vps34 activity and has been shown to induce the expression of chemokines CCL5 and CXCL10 through the STAT1/IRF7 signaling pathway. Additionally, SB02024 exhibits anticancer properties, making it a valuable tool for research in cancer biology and autophagy-related studies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2126737-28-6
Applications Vps34 Inhibitor
Formula C16H22F3N3O2
Molecular Weight 345.36
SMILES
O=C1C=C(N2[C@H](C)COCC2)C=C(N3[C@@H](C(F)(F)F)CCCC3)N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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