SB1317 (TG02)

Catalog No.: A13454

CDK/JAK2/FLT3 inhibitor

SB1317 (TG02) Chemical Structure

CAS NO. 1204918-72-8

SB1317 is a potent inhibitor of Cyclin dependent kinases (CDKs), FMS-like tyrosine kinase-3 (FLT3) and Janus kinase 2 (JAK2) with IC50 values of 13nM, 56nM and 73nM for CDK2, JAK2 and FLT3, respectively.

Availability: In stock

Package Price Qty
5 mg
$140.00
10 mg
$220.00
50 mg
$500.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SB1317 is a potent inhibitor of Cyclin dependent kinases (CDKs), FMS-like tyrosine kinase-3 (FLT3) and Janus kinase 2 (JAK2) with IC50 values of 13nM, 56nM and 73nM for CDK2, JAK2 and FLT3, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.85 mL 134.24 mL 268.49 mL
0.5 mM 5.37 mL 26.85 mL 53.7 mL
1 mM 2.68 mL 13.42 mL 26.85 mL
5 mM 0.54 mL 2.68 mL 5.37 mL

*The above data is based on the productmolecular weight 372.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13454
Actions Inhibitor
M. Wt 372.46
Formula C23H24N4O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1204918-72-8
Synonyms 0
SMILES CN(C/C=C/CCOC1=CC=CC2=C1)CC3=CC(NC4=NC=CC2=N4)=CC=C3

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