Fig. 1 · Structure
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SC-51316
Angiotensin II Receptor Antagonist
SC-51316 is an orally active angiotensin II receptor antagonist, demonstrating IC50 values of 3.6 nM in rat adrenal cortical membranes and 5.1 nM in rat uterine membranes. This compound exhibits significant antihypertensive effects both in vivo and in vitro, making it a valuable tool for research into cardiovascular conditions and related therapeutic interventions. Its targeting of the angiotensin II pathway opens avenues for investigating hypertension and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 133690-62-7 |
| Applications | Angiotensin II Receptor Antagonist |
| Formula | C24H29N7O |
| Molecular Weight | 431.53 |
| SMILES | O=C1N(CCCC)N=C(CCCC)N1CC2=CC=C(C3=C(C4=NN=NN4)C=CC=C3)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.