Fig. 1 · Structure
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Scaff10-8
RhoA Inhibitor
Scaff10-8 is a selective RhoA inhibitor that effectively disrupts AKAP-Lbc-mediated RhoA activation. This compound demonstrates potent biological activity by preventing downstream signaling pathways associated with RhoA, making it a valuable tool for investigating RhoA-related cellular processes. It is suitable for research applications such as studying cytoskeletal dynamics and cell migration.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 777857-56-4 |
| Applications | RhoA Inhibitor |
| Formula | C22H18O6 |
| Molecular Weight | 378.37 |
| SMILES | O=C(CCC1=C(C2=CC3=C(C=C2OC1=O)OC=C3C4=CC=C(C=C4)OC)C)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.