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SCH-23390

Dopamine Receptor Antagonists

SCH-23390 is a potent antagonist of dopamine D1-like receptors, exhibiting Ki values of 0.2 nM for the D1 subtype and 0.3 nM for the D5 subtype. This compound plays a significant role in behavioral research by shortening the latency period for cocaine-induced lever pressing in rat models. Additionally, SCH-23390 has been shown to eliminate generalized seizures induced by chemical convulsants, making it valuable in the study of neurological disorders associated with the dopamine system.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	87075-17-0
Applications	Dopamine Receptor Antagonists
Formula	C₁₇H₁₈ClNO
Molecular Weight	287.78
Synonyms	R-(+)-SCH-23390
SMILES	OC1=C(Cl)C=C2CCN(C)C[C@H](C3=CC=CC=C3)C2=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.