SCH-720881 is the active metabolite of Rolapitant, a selective and long-acting neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. This compound exhibits significant anti-emetic properties, making it valuable for studies involving nausea and vomiting. SCH-720881 provides insights into the pharmacological effects of NK1 receptor modulation in various preclinical models, thereby facilitating research into anti-emetic therapies.
SCH-720881 is the active metabolite of Rolapitant, a selective and long-acting neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. This compound exhibits significant anti-emetic properties, making it valuable for studies involving nausea and vomiting. SCH-720881 provides insights into the pharmacological effects of NK1 receptor modulation in various preclinical models, thereby facilitating research into anti-emetic therapies.
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