Fig. 1 · Structure
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Schnurri-3 inhibitor-1
Shn3 Inhibitor
Schnurri-3 inhibitor-1 is a selective inhibitor of Schnurri-3 (Shn3), an important regulator of bone formation in adults. With an AC50 value of 2.09 μM in the Shn3FFL osteoblast cell line utilizing the EF1alpha promoter, this compound effectively modulates Shn3 activity. Schnurri-3 inhibitor-1 is applicable in studies focused on osteoporosis and related bone disorders, providing insights into potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 736154-60-2 |
| Applications | Shn3 Inhibitor |
| Formula | C12H10F2N2O2S |
| Molecular Weight | 284.28 |
| SMILES | O=S(NCC1=CC=NC=C1)(C2=CC=C(C(F)=C2)F)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.