SCL-1 is an orally active inhibitor of the PD-1/PD-L1 pathway, effectively blocking the interaction between PD-1 and PD-L1. This compound enhances the proliferation of T cells, B cells, and natural killer cells, contributing to robust antitumor activity. SCL-1 mediates tumor growth inhibition through the induction of effector T cells within the tumor environment and by upregulating long non-coding RNAs that act as neoantigens, facilitating cytotoxic T lymphocyte activation. This reagent is valuable for cancer research, particularly in studies focused on triple-negative breast cancer.
SCL-1 is an orally active inhibitor of the PD-1/PD-L1 pathway, effectively blocking the interaction between PD-1 and PD-L1. This compound enhances the proliferation of T cells, B cells, and natural killer cells, contributing to robust antitumor activity. SCL-1 mediates tumor growth inhibition through the induction of effector T cells within the tumor environment and by upregulating long non-coding RNAs that act as neoantigens, facilitating cytotoxic T lymphocyte activation. This reagent is valuable for cancer research, particularly in studies focused on triple-negative breast cancer.
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