Fig. 1 · Structure
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SCP1-IN-2
SCP1 Inhibitor
SCP1-IN-2 is a potent and selective covalent inhibitor of SCP1, effectively promoting the degradation of REST protein while reducing its transcriptional activity. Elevated levels of REST are implicated in the proliferation of certain glioblastoma cells, making SCP1-IN-2 a valuable tool for studying glioblastoma driven by REST-mediated transcription. This compound holds promise for advancing research in cancer biology and therapeutic interventions targeting REST-driven tumors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2764615-56-5 |
| Applications | SCP1 Inhibitor |
| Formula | C19H17F3N2O6S2 |
| Molecular Weight | 490.47 |
| SMILES | O=S1(C2=CC=CC=C2C=C1C(NCCCNS(C3=CC=C(C=C3)OC(F)(F)F)(=O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.