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SDH-IN-36

SDHC Inhibitor

SDH-IN-36 is a selective inhibitor of SDHC, exerting its effects through the enhancement of reactive oxygen species (ROS) and the induction of apoptosis via disruption of electron transfer. This compound demonstrates potent anti-proliferative activity against various tumor cell lines, including SSK4 (GI50 = 0.156 µM), SSNU638 (GI50 = 0.659 µM), and SKATOIII (GI50 = 0.490 µM). SDH-IN-36 shows potential for further research in the treatment of cancers, particularly gastric cancer, by significantly inhibiting tumor growth.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	261929-60-6
Applications	SDHC Inhibitor
Formula	C₃₁H₅₃NO₃
Molecular Weight	487.76
SMILES	CC1=C2CC[C@](OC2=C(C(C)=C1OCC(N)=O)C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.