Fig. 1 · Structure
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SDI-118
SV2A Modulator
SDI-118 is an orally active modulator targeting synaptic vesicle glycoprotein 2A (SV2A), exhibiting an IC50 of 13 nM. This compound influences synaptic transmission and is utilized in research focused on neurological disorders and synaptic plasticity. SDI-118's role in modulating SV2A provides valuable insights into potential therapeutic strategies for various conditions affecting the central nervous system.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1651179-19-9 |
| Applications | SV2A Modulator |
| Formula | C13H10ClF3N4O |
| Molecular Weight | 330.69 |
| SMILES | O=C1C[C@H](C2=CC(F)=C(C(F)=C2)F)CN1CN3C(Cl)=NC=N3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.