Fig. 1 · Structure

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SDZ 208-912

5-HT Receptor Agonist/Dopamine Receptor Antagonist

SDZ 208-912 is a dual-action compound functioning as a 5-HT1A/2 receptor agonist and a dopamine D1 receptor antagonist. It demonstrates partial dopamine agonism along with atypical neurosedative effects in rodent models. This reagent is valuable for investigating neurological disorders, particularly in the context of schizophrenia research.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 101000-49-1
Applications 5-HT Receptor Agonist/Dopamine Receptor Antagonist
Formula C20H26ClN3O
Molecular Weight 359.89
SMILES
ClC1=C2C3=C(N1)C=CC=C3[C@]4([H])[C@@](N(C[C@H](C4)NC(C(C)(C)C)=O)C)([H])C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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