Fig. 1 · Structure
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Sec61-IN-1
sec61 Ihibitor
Sec61-IN-1 is a potent inhibitor of the Sec61 translocon, which plays a critical role in protein translocation and folding. This compound demonstrates significant anti-glioma activity and has been shown to enhance T cell cytotoxicity against cancer cells. Sec61-IN-1 is valuable for research applications focusing on cancer immunotherapy and the study of cellular protein dynamics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2484865-42-9 |
| Applications | sec61 Ihibitor |
| Formula | C23H22N6OS |
| Molecular Weight | 430.53 |
| SMILES | O=C(C1=CC=CN1CC2=CC=NC=C2)NC3=NC([C@@H]4N(C5=NC=CC=C5)CCC4)=CS3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.