Fig. 1 · Structure
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Sec61-IN-2
Protein Secretion Inhibitor
Sec61-IN-2 is a potent protein secretion inhibitor that targets the Sec61 translocon complex, crucial for the translocation of nascent proteins into the endoplasmic reticulum. This compound effectively interferes with protein secretion pathways, making it a valuable tool in studies of cellular protein dynamics and the regulation of secretory mechanisms. Its applications extend to research on diseases characterized by dysregulated protein secretion, providing insights into potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2484865-72-5 |
| Applications | Protein Secretion Inhibitor |
| Formula | C22H19N5OS |
| Molecular Weight | 401.48 |
| SMILES | O=C(C1=CC=CN1CC2=CC=NC=C2)NC3=NC(/C=C/C4=NC=CC=C4C)=CS3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.