Fig. 1 · Structure
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Sec61-IN-3
Protein Secretion Inhibitor
Sec61-IN-3 is a potent inhibitor of the Sec61 translocon, a critical component in the protein secretion pathway. This compound effectively disrupts protein translocation, thereby inhibiting the secretion of proteins from the endoplasmic reticulum. Its activity makes Sec61-IN-3 valuable for research into protein transport mechanisms and the regulation of cellular secretory processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2484862-54-4 |
| Applications | Protein Secretion Inhibitor |
| Formula | C25H26N4O2S |
| Molecular Weight | 446.56 |
| SMILES | O=C(C1=CC=CN1CC2=CC=NC=C2)NC3=NC(C(OC(C4=CC=CC=C4)C)(C)C)=CS3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.