Fig. 1 · Structure
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Seco Rapamycin
Rapamycin Ring-Opened Product
Seco Rapamycin, the ring-opened derivative of Rapamycin, serves as a significant tool in biochemical research. Unlike its parent compound, Seco Rapamycin does not inhibit the mTOR pathway, making it valuable for studies that require mTOR-independent effects. This compound is useful in assessing the biological activities of Rapamycin and exploring alternative pathways influenced by its structural modifications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 147438-27-5 |
| Applications | Rapamycin Ring-Opened Product |
| Formula | C51H79NO13 |
| Molecular Weight | 914.17 |
| Synonyms | Secorapamycin A |
| SMILES | O=C([C@H]1N(C(C([C@@]2(O)[C@H](C)CC[C@@H](C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C([C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(/C=C/[C@H](C)C[C@H]3C[C@@H](OC)[C@H](O)CC3)=O)=O)O2)=O)=O)CCCC1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.