Fig. 1 · Structure
Documents & Downloads
Seconeolitsine
TopA Inhibitor
Seconeolitsine is a potent inhibitor of topoisomerase I (TopA), demonstrating antimicrobial properties against Streptococcus pneumoniae. With an IC50 value of 17 μM, Seconeolitsine effectively inhibits the relaxation activity of TopA, making it a valuable tool for studying bacterial infections, particularly those exhibiting resistance to conventional antibiotics. Its unique mechanism of action positions it as a promising candidate in the exploration of new therapeutic strategies for combating antibiotic-resistant pathogens.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2650074-56-7 |
| Applications | TopA Inhibitor |
| Formula | C19H17NO4 |
| Molecular Weight | 323.34 |
| SMILES | CNCCC1=C2C=CC3=CC(OCO4)=C4C=C3C2=C5OCOC5=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.