Fig. 1 · Structure
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sEH inhibitor-1
sEH Inhibitor
sEH inhibitor-1 is a potent inhibitor of soluble epoxide hydrolase (sEH) that demonstrates IC50 values of 0.4 nM in human and 5.3 nM in murine systems. This compound effectively modulates the metabolism of epoxyeicosanoids, offering potential therapeutic implications in the regulation of inflammation, pain, and cardiovascular diseases. It serves as a valuable tool for research applications focused on sEH inhibition and its effects on various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1208549-68-1 |
| Applications | sEH Inhibitor |
| Formula | C17H20F3N3O3 |
| Molecular Weight | 371.35 |
| SMILES | O=C(NC1=CC=C(C=C1)OC(F)(F)F)NC2CCN(CC2)C(C3CC3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.