Fig. 1 · Structure

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sEH inhibitor-2

sEH Inhibitor

sEH inhibitor-2 is a potent soluble epoxide hydrolase (sEH) inhibitor with an IC50 value of 0.9 nM. It demonstrates high oral bioavailability and effectively maintains elevated serum levels of epoxyeicosatrienoic acids (EETs). This compound is essential for investigating mechanisms of cardiovascular protection and related therapeutic applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2816102-69-7
Applications sEH Inhibitor
Formula C23H18N4O3
Molecular Weight 398.41
SMILES
O=C(C1=CC=CC=C1C(NC2=CC=C(C=C2)CN3C=C(N=N3)C4=CC=CC=C4)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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