Fig. 1 · Structure
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sEH inhibitor-5
sEH Inhibitor
sEH inhibitor-5 is a highly potent soluble epoxide hydrolase (sEH) inhibitor, demonstrating an IC50 value of 0.1 nM. Its primary mechanism involves the selective inhibition of the sEH enzyme, which plays a crucial role in regulating eicosanoid metabolism. This compound is valuable for research applications investigating the modulation of inflammation and cardiovascular function, making it an essential tool for studies related to metabolic disorders and vascular health.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2752467-28-8 |
| Applications | sEH Inhibitor |
| Formula | C27H26Cl2N6O3S |
| Molecular Weight | 585.50 |
| SMILES | O=C(NC1=NC2=CC=C(C=C2S1)N(C(NC3=CC=C(C=C3)Cl)=O)CCN4CCOCC4)NC5=CC=C(C=C5)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.