Fig. 1 · Structure
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sEH inhibitor-7
sEH Inhibitor
sEH inhibitor-7 is a potent inhibitor of soluble epoxide hydrolase (sEH), exhibiting IC50 values of 0.15 μM for mouse sEH and 6.2 μM for human sEH. By targeting sEH, this compound plays a significant role in modulating the metabolism of endogenous epoxyeicosanoids, which are critical in regulating blood pressure and inflammatory responses. This reagent is valuable for research applications focused on cardiovascular health and inflammation pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 340221-20-7 |
| Applications | sEH Inhibitor |
| Formula | C15H21NO2 |
| Molecular Weight | 247.33 |
| SMILES | O=C(NC1=CC=C(OC)C=C1)CC2CCCCC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.