Fig. 1 · Structure
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Selatogrel
P2Y Receptor Antagonist
Selatogrel is a reversible and selective P2Y12 receptor antagonist, effectively inhibiting platelet aggregation with an IC50 of 8 nM. This compound demonstrates significant antithrombotic activity, making it a valuable tool for research in cardiovascular disease, particularly in studies focused on thrombus formation and prevention. Selatogrel's specific mechanism of action allows for targeted investigations into the role of platelet inhibition in various pathological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1159500-34-1 |
| Applications | P2Y Receptor Antagonist |
| Formula | C28H39N6O8P |
| Molecular Weight | 618.62 |
| Synonyms | ACT-246475 |
| SMILES | O=C(N1CCN(CC1)C(OCCCC)=O)[C@H](CP(O)(O)=O)NC(C2=CC(N3C[C@H](CC3)OC)=NC(C4=CC=CC=C4)=N2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.