Fig. 1 · Structure
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Selenodiglutathione
Selenium Metabolite
Selenodiglutathione (GSSeSG) is a selenotrisulfide and key selenium metabolite conjugated with two glutathione units. This compound induces DNA damage, including base oxidation and strand breaks, while promoting apoptosis in target cells. Selenodiglutathione demonstrates notable cytotoxicity against breast cancer cells through preferential cellular uptake and increased intracellular selenium concentrations. It is particularly valuable for research focused on breast cancer mechanisms and therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 33944-90-0 |
| Applications | Selenium Metabolite |
| Formula | C20H32N6O12S2Se |
| Molecular Weight | 691.59 |
| Synonyms | GSSeSG |
| SMILES | OC([C@@H](N)CCC(N[C@H](C(NCC(O)=O)=O)CS[Se]SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.