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SEN 78702

α7 nAChR Agonist

SEN 78702 is an orally active, selective full agonist of the α7 nicotinic acetylcholine receptor (nAChR) with a pEC50 of 6.13. This compound is known to enhance memory functions, making it a valuable tool for research in cognitive disorders. Additionally, SEN 78702 exhibits an acceptable level of hERG inhibition (IC50: 15.8 μM), indicating its potential for further pharmacological investigations.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	1205530-63-7
Applications	α7 nAChR Agonist
Formula	C₁₇H₂₂FN₅O
Molecular Weight	331.39
SMILES	O=C(NC1=CC(C2=CC(F)=CN=C2)=NN1)CCCN3CCCCC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.