Fig. 1 · Structure
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Senkirkin
Cat. No.
A69801
CAS
2318-18-5
CYP3A4 Substrate
Senkirkin is a pyrrolizidine alkaloid that serves as a substrate for the cytochrome P450 enzyme CYP3A4. It has been shown to induce chromosomal damage in lymphocytes, highlighting its potential utility in toxicological studies. This compound can be leveraged in research applications involving drug metabolism and the assessment of genotoxicity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 2318-18-5 |
| Applications | CYP3A4 Substrate |
| Formula | C19H27NO6 |
| Molecular Weight | 365.42 |
| Synonyms | Senkirkine; Renardin |
| SMILES | O=C(/C(C[C@@H](C)[C@]1(O)C)=C\C)O[C@](C2=O)([H])CCN(C)C/C=C2/COC1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.