SEP-363856 mesylate

Catalog No.: A29748
TAAR1/5-HT1A Agonist
SEP-363856 mesylate is a selective agonist for the trace amine-associated receptor 1 (TAAR1) and the 5-HT1A receptor, exhibiting unique psychotropic effects through a non-dopaminergic mechanism of action. This compound demonstrates antipsychotic-like activity, making it a valuable tool for investigating the pathophysiology and treatment of schizophrenia. Its distinct mechanism provides a novel approach to research in mental health disorders, particularly in areas where traditional therapies may be ineffective.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSEP-363856 mesylate is a selective agonist for the trace amine-associated receptor 1 (TAAR1) and the 5-HT1A receptor, exhibiting unique psychotropic effects through a non-dopaminergic mechanism of action. This compound demonstrates antipsychotic-like activity, making it a valuable tool for investigating the pathophysiology and treatment of schizophrenia. Its distinct mechanism provides a novel approach to research in mental health disorders, particularly in areas where traditional therapies may be ineffective.
Product Information
Catalog NumA29748
FormulaC10H17NO4S2
Molecular Weight279.38
CAS Number2375116-27-9
SMILESCS(=O)(O)=O.CNC[C@H]1C2=C(CCO1)C=CS2
SynonymsSEP-856 mesylate
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