Fig. 1 · Structure
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Sepimostat dimethanesulfonate
Neuroprotective Agent
Sepimostat dimethanesulfonate is a neuroprotective agent that functions as an antagonist of the NR2B N-methyl-D-aspartate (NMDA) receptor at the Ifenprodil-binding site of the NR2B subunit. This compound demonstrates significant inhibitory activity towards Ifenprodil binding, with a Ki value of 27.7 µM. Its neuroprotective properties indicate potential applications in research focused on neurodegenerative diseases and neuroprotection interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 103926-82-5 |
| Applications | Neuroprotective Agent |
| Formula | C23H27N5O8S2 |
| Molecular Weight | 565.62 |
| Synonyms | FUT-187 |
| SMILES | O=C(OC1=CC=C2C=C(C(N)=N)C=CC2=C1)C3=CC=C(NC4=NCCN4)C=C3.CS(=O)(O)=O.CS(=O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.