Fig. 1 · Structure
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Sepimostat
Neuroprotective Agent
Sepimostat is a neuroprotective agent that functions as an antagonist at the NR2B subunit of the N-methyl-D-aspartate (NMDA) receptor, specifically at the Ifenprodil-binding site. This compound demonstrates significant neuroprotective activity, inhibiting Ifenprodil binding with a Ki value of 27.7 μM. Sepimostat's mechanism makes it a valuable tool in research focused on neurodegenerative diseases and synaptic function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 103926-64-3 |
| Applications | Neuroprotective Agent |
| Formula | C21H19N5O2 |
| Molecular Weight | 373.41 |
| Synonyms | FUT-187 free base |
| SMILES | O=C(OC1=CC=C2C=C(C(N)=N)C=CC2=C1)C3=CC=C(NC4=NCCN4)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.