Sergolexole maleate

Catalog No.: A29622
5-HT2 Receptor Antagonist
Sergolexole maleate is a potent antagonist of the 5-HT2 receptor, which plays a crucial role in various serotonin-mediated physiological processes. This compound exhibits significant inhibitory effects on serotonin-enhanced platelet aggregation, making it relevant for research into cardiovascular function and platelet behavior. Its role in modulating serotonin activity positions Sergolexole maleate as a valuable tool for exploring mechanisms associated with mood disorders and thrombotic conditions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSergolexole maleate is a potent antagonist of the 5-HT2 receptor, which plays a crucial role in various serotonin-mediated physiological processes. This compound exhibits significant inhibitory effects on serotonin-enhanced platelet aggregation, making it relevant for research into cardiovascular function and platelet behavior. Its role in modulating serotonin activity positions Sergolexole maleate as a valuable tool for exploring mechanisms associated with mood disorders and thrombotic conditions.
Product Information
Catalog NumA29622
FormulaC30H40N2O7
Molecular Weight540.65
CAS Number108674-87-9
SMILESOC(/C=C\C(O)=O)=O.CC(N1C2=C3C([C@]4([H])[C@@](N(C[C@@H](C4)C(O[C@@H]5CC[C@H](CC5)OC)=O)C)([H])CC3=C1)=CC=C2)C
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