(-)-Sesamin 2,2'-diol is a nitric oxide (NO) production inhibitor, exhibiting an IC50 of 310 μM against LPS-induced NO production. This compound, isolated from the aerial parts of Isodon japonicus, effectively suppresses NO synthesis in LPS-stimulated macrophages while demonstrating a lack of cytotoxic effects. Its properties make it a valuable tool for research focusing on inflammatory responses and nitric oxide signaling pathways.
(-)-Sesamin 2,2'-diol is a nitric oxide (NO) production inhibitor, exhibiting an IC50 of 310 μM against LPS-induced NO production. This compound, isolated from the aerial parts of Isodon japonicus, effectively suppresses NO synthesis in LPS-stimulated macrophages while demonstrating a lack of cytotoxic effects. Its properties make it a valuable tool for research focusing on inflammatory responses and nitric oxide signaling pathways.
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