Fig. 1 · Structure
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Sevasemten
Myosin Inhibitor
Sevasemten is a selective allosteric inhibitor targeting skeletal muscle myosin. It demonstrates significant protective effects against contraction-induced injury in skeletal muscle, contributing to a decrease in muscle damage biomarkers and fibrosis. Additionally, sevasemten enhances muscle strength and activity in models of Duchenne muscular dystrophy, making it a valuable tool for research applications related to muscle degeneration and recovery.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2417395-15-2 |
| Applications | Myosin Inhibitor |
| Formula | C16H11F4N5O2 |
| Molecular Weight | 381.28 |
| Synonyms | EDG-5506 |
| SMILES | O=C1C=CC(C2=CN=C(OCC(F)(F)F)N=C2)=NN1CC3=CC(F)=CN=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.