Fig. 1 · Structure
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Sevelamer carbonate
Phosphate Binding Agent
Sevelamer carbonate is a non-calcium-based phosphate binding agent primarily targeting hyperphosphatemia associated with chronic kidney disease (CKD). It is effective in lowering serum phosphorus levels while exerting minimal impact on serum calcium and chloride levels in vivo. Sevelamer carbonate offers an improved, buffered formulation compared to traditional sevelamer, making it a valuable tool for researchers studying phosphate regulation and metabolic management in kidney disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 845273-93-0 |
| Applications | Phosphate Binding Agent |
| Formula | (C3H7N.C3H5ClO)x.xH2CO3 |
| SMILES | NCC(CC(CC)CNCC(O)CNCC(C)CC(CC)CN)CC.[m].[c].[b].[a].[m H2CO3] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.