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Form	MW
Sezolamide This page	338.47
Sezolamide hydrochloride	374.93

Sezolamide

Carbonic Anhydrase Inhibitor

Sezolamide is a potent inhibitor of carbonic anhydrase, primarily utilized for its ability to reduce intraocular pressure. Its mechanism of action involves the inhibition of carbonic anhydrase enzymes, which play a critical role in the regulation of bicarbonate and fluid balance in ocular tissues. This compound is valuable in research studies focused on glaucoma and other conditions associated with elevated intraocular pressure.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	123308-22-5
Applications	Carbonic Anhydrase Inhibitor
Formula	C₁₁H₁₈N₂O₄S₃
Molecular Weight	338.47
Synonyms	MK 417 free base; (S)-MK-927 free base
SMILES	O=S1(C2=C(C=C(S2)S(N)(=O)=O)[C@H](CC1)NCC(C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.