Fig. 1 · Structure
Documents & Downloads
SG2057
PBD Dimer
SG2057 is a PBD dimer that features a pentyldioxy linkage, enabling selective binding to the minor groove of DNA. This compound forms DNA interstrand and intrastrand cross-linked adducts, which contribute to its potent antitumor activity. SG2057 serves as a valuable tool for research applications focused on cancer therapeutics and the mechanisms of DNA damage and repair.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 260417-62-7 |
| Applications | PBD Dimer |
| Formula | C33H36N4O6 |
| Molecular Weight | 584.66 |
| Synonyms | DRG16 |
| SMILES | O=C1N2[C@](CC(C2)=C)([H])C=NC3=CC(OCCCCCOC4=C(OC)C=C5C(N6[C@](CC(C6)=C)([H])C=NC5=C4)=O)=C(OC)C=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.