Fig. 1 · Structure

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SG3376

ADC

SG3376 is an antibody-drug conjugate (ADC) that specifically targets the human epidermal growth factor receptor 2 (HER2). This compound demonstrates significant potential in the treatment of HER2-overexpressing cancers, such as breast and gastric cancers, by delivering cytotoxic agents directly to cancer cells. SG3376 serves as a valuable tool for research aimed at understanding and developing therapies for HER2-positive tumors.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2139261-06-4
Applications ADC
Formula C57H63N7O14
Molecular Weight 1070.15
SMILES
O=C1C2=CC(OC)=C(OCC3=CC(COC4=C(C=C5C(N=C[C@@]6([H])N(C=C(C6)C)C5=O)=C4)OC)=CC(C#CCNC(CCOCCOCCOCCOCCNC(CCN7C(C=CC7=O)=O)=O)=O)=C3)C=C2N=C[C@@]8([H])N1C=C(C8)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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