SGB-1534 hydrochloride

Catalog No.: A29894
α1/5-HT2 Receptor Antagonist
SGB-1534 hydrochloride is a selective and competitive antagonist of the alpha 1-adrenoceptor and the 5-HT2 receptor. This compound demonstrates the ability to inhibit vasoconstriction, resulting in lowered blood pressure, making it a valuable tool in cardiovascular research. SGB-1534 hydrochloride is particularly relevant for investigating conditions such as hypertension and other related cardiovascular diseases.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSGB-1534 hydrochloride is a selective and competitive antagonist of the alpha 1-adrenoceptor and the 5-HT2 receptor. This compound demonstrates the ability to inhibit vasoconstriction, resulting in lowered blood pressure, making it a valuable tool in cardiovascular research. SGB-1534 hydrochloride is particularly relevant for investigating conditions such as hypertension and other related cardiovascular diseases.
Product Information
Catalog NumA29894
FormulaC21H25ClN4O3
Molecular Weight416.90
CAS Number88068-72-8
SMILESO=C(N1CCN2CCN(C3=C(C=CC=C3)OC)CC2)C4=CC=CC=C4NC1=O.Cl
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