Fig. 1 · Structure
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SGC-STK17B-1
STK17B Inhibitor
SGC-STK17B-1 is a selective and ATP-competitive inhibitor of STK17B, a member of the death-associated protein kinase family. With an IC50 of 34 nM and a KD of 5.6 nM, this compound is suitable for investigating the biological roles of STK17B in various cellular contexts. SGC-STK17B-1 is primarily utilized in research applications focused on cell death, apoptosis, and related signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2650530-00-8 |
| Applications | STK17B Inhibitor |
| Formula | C16H10N2O2S3 |
| Molecular Weight | 358.46 |
| SMILES | O=C(CSC1=NC=NC2=C1SC(C3=CC4=C(C=CC=C4)S3)=C2)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.