Fig. 1 · Structure
Documents & Downloads
SGE-516
GABA Receptor Modulator
SGE-516 is a neuroactive steroid functioning as a potent positive allosteric modulator of both synaptic and extra-synaptic GABAA receptors. This compound exhibits significant anticonvulsant activity, making it a valuable tool for research in neurological disorders, especially those related to GABAergic signaling. Its modulatory effects can provide insights into therapeutic strategies for epilepsy and other conditions characterized by altered GABA receptor function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1430064-74-6 |
| Applications | GABA Receptor Modulator |
| Formula | C23H35N3O2 |
| Molecular Weight | 385.54 |
| SMILES | C[C@@]12[C@@H](C(CN3N=CC=N3)=O)CC[C@@]1([H])[C@]4([H])CC[C@]5([H])C[C@](C)(O)CC[C@]5([H])[C@@]4([H])CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.