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SGE-516

Catalog No.: A66970
GABA Receptor Modulator
SGE-516 is a neuroactive steroid functioning as a potent positive allosteric modulator of both synaptic and extra-synaptic GABAA receptors. This compound exhibits significant anticonvulsant activity, making it a valuable tool for research in neurological disorders, especially those related to GABAergic signaling. Its modulatory effects can provide insights into therapeutic strategies for epilepsy and other conditions characterized by altered GABA receptor function.
SGE-516 1430064-74-6 GABA Receptor Modulator
Grouped product items
Size Price Stock Qty
25mg
$1,780.00
In stock
50mg
$2,280.00
In stock
100mg
$2,960.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSGE-516 is a neuroactive steroid functioning as a potent positive allosteric modulator of both synaptic and extra-synaptic GABAA receptors. This compound exhibits significant anticonvulsant activity, making it a valuable tool for research in neurological disorders, especially those related to GABAergic signaling. Its modulatory effects can provide insights into therapeutic strategies for epilepsy and other conditions characterized by altered GABA receptor function.
Product Information
Catalog NumA66970
FormulaC23H35N3O2
Molecular Weight385.54
CAS Number1430064-74-6
SMILESC[C@@]12[C@@H](C(CN3N=CC=N3)=O)CC[C@@]1([H])[C@]4([H])CC[C@]5([H])C[C@](C)(O)CC[C@]5([H])[C@@]4([H])CC2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Neuronal Signaling > GABA Receptors