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SH379

Anti-late-onset Hypogonadism Agent

SH379 is a derivative of 2-methylpyrimidine-fused tricyclic diterpene targeting late-onset hypogonadism. This compound is a potent and orally active agent that enhances the expression of critical testosterone synthesis enzymes, including StAR and 3β-HSD. Additionally, SH379 stimulates autophagy by modulating the AMPK/mTOR signaling pathway, making it a valuable tool for research into testosterone-related conditions and metabolic regulation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2338793-00-1
Applications	Anti-late-onset Hypogonadism Agent
Formula	C₂₃H₂₉N₃O₂
Molecular Weight	379.50
SMILES	C[C@@]12C3=CC(OC)=C(C(NC)=O)C=C3CC[C@@]1([H])C(C)(C4=NC(C)=NC=C4C2)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.