Fig. 1 · Structure
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SH6
ZBTB7A Degrader
SH6 is a targeted degrader of the transcription factor ZBTB7A. This compound demonstrates significant potential in the study of β-hemoglobinopathies, including sickle cell disease (SCD) and β-thalassemia. By modulating ZBTB7A levels, SH6 may provide insights into the underlying mechanisms of these disorders and facilitate the development of novel therapeutic approaches.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2619408-35-2 |
| Applications | ZBTB7A Degrader |
| Formula | C23H23ClN4O4 |
| Molecular Weight | 454.91 |
| SMILES | O=C(NC1=C(N)C=C(Cl)C=C1)/C=C/C2=C(NC3=CC(OC)=C(OC)C(OC)=C3)N=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.