Fig. 1 · Structure
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SHP2 protein degrader-1
SHP2 Inhibitor
SHP2 protein degrader-1 is a potent allosteric inhibitor targeting the SHP2 protein, which plays a significant role in various signaling pathways. This compound induces degradation of SHP2, leading to programmed cell death (apoptosis) in affected cells. SHP2 protein degrader-1 is valuable for research into SHP2-related diseases, including cancers and other pathologies where SHP2 dysregulation contributes to disease progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2624181-69-5 |
| Applications | SHP2 Inhibitor |
| Formula | C42H51Cl2N11O8 |
| Molecular Weight | 908.83 |
| SMILES | O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCOCCN4N=NC(CNC5(CCN(CC5)C6=CN=C(C7=C(Cl)C(Cl)=CC=C7)C(N)=N6)C)=C4)=CC=C3)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.