Fig. 1 · Structure
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SHS4121705
Mitochondrial uncoupling Agent
SHS4121705 is a mitochondrial uncoupling agent that effectively increases metabolic rate by dissipating the proton gradient across the inner mitochondrial membrane. With an IC50 of 4.3 μM in L6 myoblasts, this compound serves as a valuable tool for investigating the mechanisms underlying non-alcoholic steatohepatitis (NASH) and related metabolic disorders. Its ability to modulate energy expenditure makes it relevant for studies focusing on obesity and metabolic syndrome.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2379550-82-8 |
| Applications | Mitochondrial uncoupling Agent |
| Formula | C11H6F3N5O3 |
| Molecular Weight | 313.19 |
| SMILES | O=C1N=C2C(N=C1NC3=CC=C(OC(F)(F)F)C=C3)=NON2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.