Fig. 1 · Structure
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SIB-1508Y
nAChR Agonist
SIB-1508Y is an orally active and selective agonist of the nicotinic acetylcholine receptor (nAChR). It holds potential for research applications related to parkinsonism and neurodegenerative disorders. Additionally, SIB-1508Y features an alkyne group, enabling its use as a click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 192231-16-6 |
| Applications | nAChR Agonist |
| Formula | C16H18N2O4 |
| Molecular Weight | 302.33 |
| SMILES | CN1[C@H](C2=CN=CC(C#C)=C2)CCC1.OC(/C=C\C(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.