Fig. 1 · Structure

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SIB-1553A free base

nAChRs Agonist

SIB-1553A free base is an orally bioavailable agonist of nicotinic acetylcholine receptors (nAChRs), exhibiting selective activity towards receptors containing the β4 subunit. This compound serves as a selective ligand for neuronal nAChRs and demonstrates significant cognitive-enhancing properties. SIB-1553A free base shows therapeutic potential for addressing symptoms associated with Alzheimer's disease and other cognitive disorders in research applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 191611-76-4
Applications nAChRs Agonist
Formula C13H19NOS
Molecular Weight 237.36
SMILES
OC1=CC=C(SCCC2N(C)CCC2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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