Fig. 1 · Structure
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SIB-1553A
nAChRs Agonist
SIB-1553A is a selective agonist of nicotinic acetylcholine receptors (nAChRs), specifically targeting β4 subunit-containing receptors. This compound exhibits neuroprotective properties and enhances cognitive function, making it a valuable tool in the study of Alzheimer’s disease and other cognitive disorders. Its oral bioavailability further supports its potential for therapeutic applications in cognitive enhancement.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 191611-89-9 |
| Applications | nAChRs Agonist |
| Formula | C13H20ClNOS |
| Molecular Weight | 273.82 |
| SMILES | OC(C=C1)=CC=C1SCCC2N(CCC2)C.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.