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Form	MW
Sibenadet This page	464.60
Sibenadet hydrochloride	501.06

Sibenadet

Dopamine D2/β2-adrenoceptor Agonist

Sibenadet is a dual agonist for dopamine D2 and β2-adrenoceptors, exhibiting selective activity at the β2-adrenoceptor. It has been shown to inhibit capsaicin-induced plasma protein extravasation in rat trachea, effectively suppressing edema resulting from sensory nerve fiber activation through β2-adrenoceptor activation. Sibenadet holds potential for advancing research into chronic obstructive pulmonary disease (COPD).

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	154189-40-9
Applications	Dopamine D2/β2-adrenoceptor Agonist
Formula	C₂₂H₂₈N₂O₅S₂
Molecular Weight	464.60
Synonyms	AR-C68397AA free base; AR-C68397XX
SMILES	O=C1SC2=C(CCNCCS(=O)(CCCOCCC3=CC=CC=C3)=O)C=CC(O)=C2N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.